Almost everyone is aware of the BRCA1/2 gene mutation and its linkage with increased risk for breast and ovarian cancer. But we now understand the BRCA mutations also can be linked with aggressive prostate cancer. Men who have these mutations in their DNA are known as germline mutations. Men who have BRCA1 mutation have up to four times greater risk of developing prostate cancer and those with BRCA2 have up to nine-fold higher risk. BRCA2 mutations have been associated with the more aggressive forms of the disease and an earlier diagnosis -- meaning diagnosed at age 55 or younger.
Source : https://santamariatimes.com/lifestyles/health-med-fit/your-cancer-answers/dr-monica-rocco-is-there-a-link-between-prostate-cancer/article_33f36142-f8b8-59b3-a169-84ed51063ddb.html